TY  - BOOK
AU  - Hanessian,Stephen
TI  - Natural products in medicinal chemistry
T2  - Methods and principles in medicinal chemistry
SN  - 9783527332182 (hbk.)
U1  - 615.19 23
PY  - 2014///]
CY  - Weinheim
PB  - Wiley-VCH
KW  - Natural products
KW  - Organic compounds
KW  - Synthesis
KW  - Pharmaceutical chemistry
KW  - Biological Products
KW  - Chemistry, Pharmaceutical
N1  - Includes bibliographical references and index; Natural products as drugs and leads to drugs: an introduction and perspectives as of the end of 2012 -- Natural product-derived and natural product-inspired compound collections -- Chemistry and biology of epothilones -- Taxol, taxoids, and related taxanes -- Camptothecin and analogs -- A short history of the discovery and development of naltrexone and other morphine derivatives -- Lincosamide antibacterials -- Platensimycin and platencin -- From natural product to new diabetes therapy: phlorizin and the discovery of SGLT2 inhibitor clinical candidates -- Aeruginosins as thrombin inhibitors -- Macrolides and antifungals via biotransformation -- Unnatural nucleoside analogs for antisense therapy -- Hybrid natural products -- Rethinking the role of natural products: function-oriented synthesis bryostatin, and bryologs -- Cyclopamine and congeners -- Hybrids, congeners, mimics and constrained variants spanning 30 
 .years of natural products chemistry: a personal retrospective
ER  -