Rosenbaum, Sara

Basic pharmacokinetics and pharmacodynamics : an integrated textbook and computer simulations / Sara Rosenbaum. - Hoboken, N.J. : John Wiley & Sons, c2011. - xviii, 430 p. : ill. ; 26 cm.

Includes bibliographical references and index.

Introduction to pharmacokinetics and pharmacodynamics -- Passage of drug through membranes -- Drug absorption -- Drug elimination -- Compartmental models -- Pharmacokinetics of an intravenous bolus injection in a one compartment model -- An intravenous bolus injection in the two compartment model -- Pharmacokinetics of extravascular drug administration -- Introduction to non-compartmental analysis -- Pharmacokinetics of the intravenous infusion in a one compartment model -- Multiple intravenous bolus injections in the one compartment model -- Multiple intermittent infusions -- Multiple oral doses -- Nonlinear pharmacokinetics -- Introduction to pharmacodynamic models and integrated pharmacokinetic- pharmacodynamics (PK-PD) models -- Mechanism based integrated pharmacokinetic-pharmacodynamic models.

9780470569061 (cloth) 0470569069 (cloth)

2010043288

101543584 DNLM


Pharmacokinetics--Textbooks.
Pharmacokinetics--Computer simulation.
Drugs--Physiological effect--Textbooks.
Drugs--Physiological effect--Computer simulation.
Pharmacokinetics.
Computer Simulation.
Pharmacological Phenomena.

RM301.5 / .R655 2011

615.7 / RSB

QV 38