Sugano, Kiyohiko. <br/><br/>
Biopharmaceutics modeling and simulations :  theory, practice, methods, and applications / 
Kiyohiko Sugano. 
 - Hoboken, N.J. :  John Wiley & Sons,  c2012. 
 - xxxv, 483 p. :  ill. ;  24 cm. 
<br/><br/>Includes bibliographical references and index. 
<br/><br/>Introduction -- Theoretical framework I : solubility -- Theoretical framework II : dissolution -- Theoretical framework III : biological membrane permeation -- Theoretical framework IV : gastrointestinal transit models and integration -- Physiology of gastrointestinal tract and other administration sites in humans and animals -- Drug parameters -- Validation of mechanistic models -- Bioequivalence and biopharmaceutical classification system -- Dose and particle size dependency -- Enabling formulations -- Food effect -- Biopharmaceutical modeling for miscellaneous cases -- Intestinal transporters -- Strategy in drug discovery and development -- Epistemology of biopharmaceutical modeling and good simulation practice. 
<br/><br/><label>ISBN: </label>9781118028681 (cloth) 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Biopharmaceutics--methods.<br/>Computer Simulation.<br/>Drug Compounding--methods.<br/>Models, Theoretical.
<br/><br/><label>LC Class. No.: </label>RM301.4  / .S84 2012 
<br/><br/><label>Dewey Class. No.: </label>615.7  / SKB