TY  - BOOK
AU  - Sugano,Kiyohiko
TI  - Biopharmaceutics modeling and simulations: theory, practice, methods, and applications 
SN  - 9781118028681 (cloth)
AV  - RM301.4 .S84 2012
U1  - 615.7 23
PY  - 2012///
CY  - Hoboken, N.J.
PB  - John Wiley & Sons
KW  - Biopharmaceutics
KW  - methods
KW  - Computer Simulation
KW  - Drug Compounding
KW  - Models, Theoretical
N1  - Includes bibliographical references and index; Introduction -- Theoretical framework I : solubility -- Theoretical framework II : dissolution -- Theoretical framework III : biological membrane permeation -- Theoretical framework IV : gastrointestinal transit models and integration -- Physiology of gastrointestinal tract and other administration sites in humans and animals -- Drug parameters -- Validation of mechanistic models -- Bioequivalence and biopharmaceutical classification system -- Dose and particle size dependency -- Enabling formulations -- Food effect -- Biopharmaceutical modeling for miscellaneous cases -- Intestinal transporters -- Strategy in drug discovery and development -- Epistemology of biopharmaceutical modeling and good simulation practice
ER  -