000 02051cam a22003854a 4500
999 _c7292
_d7292
001 16502314
003 BUC
005 20200716131755.0
008 200716s2011 njua g b i 001 0 eng
010 _a2010043288
016 7 _a101543584
_2DNLM
020 _a9780470569061 (cloth)
020 _a0470569069 (cloth)
035 _a(OCoLC)ocn671385962
040 _aDNLM/DLC
_cDLC
_dYDX
_dNLM
_dYDXCP
_dDLC
041 0 _aeng
042 _apcc
050 0 0 _aRM301.5
_b.R655 2011
060 1 0 _aQV 38
082 0 0 _a615.7
_222
_bRSB
100 1 _aRosenbaum, Sara
_q(Sara E.)
245 1 0 _aBasic pharmacokinetics and pharmacodynamics :
_ban integrated textbook and computer simulations /
_cSara Rosenbaum.
260 _aHoboken, N.J. :
_bJohn Wiley & Sons,
_cc2011.
300 _axviii, 430 p. :
_bill. ;
_c26 cm.
504 _aIncludes bibliographical references and index.
505 0 _aIntroduction to pharmacokinetics and pharmacodynamics -- Passage of drug through membranes -- Drug absorption -- Drug elimination -- Compartmental models -- Pharmacokinetics of an intravenous bolus injection in a one compartment model -- An intravenous bolus injection in the two compartment model -- Pharmacokinetics of extravascular drug administration -- Introduction to non-compartmental analysis -- Pharmacokinetics of the intravenous infusion in a one compartment model -- Multiple intravenous bolus injections in the one compartment model -- Multiple intermittent infusions -- Multiple oral doses -- Nonlinear pharmacokinetics -- Introduction to pharmacodynamic models and integrated pharmacokinetic- pharmacodynamics (PK-PD) models -- Mechanism based integrated pharmacokinetic-pharmacodynamic models.
650 0 _aPharmacokinetics
_vTextbooks.
650 0 _aPharmacokinetics
_xComputer simulation.
650 0 _aDrugs
_xPhysiological effect
_vTextbooks.
650 0 _aDrugs
_xPhysiological effect
_xComputer simulation.
650 1 2 _aPharmacokinetics.
650 2 2 _aComputer Simulation.
650 2 2 _aPharmacological Phenomena.
942 _2ddc
_cBK