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Chapter 26  The Urinary System   1033

Figure 26–19  The Histology of the Ureter, Urinary Bladder, and Urethra.

                                                                                                                     Transitional       Mucosa
                                                                                                                     epithelium

                                                                                                                     Lamina
                                                                                                                     propria

                                                                                                                     Smooth
                                                                                                                     muscle

                                                                                                                     Outer connective
                                                                                                                     tissue layer

                                                                        Ureter                              LM × 65

                                                                        a A transverse section through the ureter.

                                                                                                                     Transitional

                                                                                                                     epithelium         Mucosa
                                                                                                                     Lamina

                                                                                                                     propria

                                                     Lumen of                                                        Submucosa
                                                     urethra
                                                                                Detrusor muscle
                                                     Smooth
                                                     muscle

Female urethra                              LM × 50  Stratified         Urinary bladder                                     Visceral
                                                     squamous           b The wall of the urinary bladder.                  peritoneum
                                                     epithelium
                                                     of mucosa                                              LM × 36

                                                     Lamina propria
                                                     containing
                                                     mucous
                                                     epithelial glands

c A transverse section through the female
   urethra. A thick layer of smooth muscle
   surrounds the lumen.

&T i p s T r i c k s                                                                                                        	26
  To remember that the urethra is the urinary tract’s pipeline to
  the exterior, proclaim, “Eureka! Your urine! It’s coming out the      into the lamina propria. Connective tissues of the lamina
  urethra!”                                                             propria anchor the urethra to surrounding structures. In fe-
                                                                        males, the lamina propria contains an extensive network of
Histology of the Urethra                                                veins. Concentric layers of smooth muscle surround the en-
                                                                        tire complex.
The urethral lining consists of a stratified epithelium that
varies from transitional epithelium at the neck of the urinary          The Micturition Reflex and Urination
bladder, to stratified columnar epithelium at the midpoint,
to stratified squamous epithelium near the external urethral            As we have seen, urine reaches the urinary bladder by peristaltic
orifice. The lamina propria is thick and elastic. The mucosa            contractions of the ureters. The micturition reflex coordinates
is folded into longitudinal creases (Figure 26–19c). Mucin-             the process of urination (Figure 26–20).
secreting cells are located in the epithelial pockets. In males,
the epithelial mucous glands may form tubules that extend                    As the bladder fills with urine, stretch receptors in the blad-
                                                                        der wall are stimulated. Afferent fibers in the pelvic nerves carry
                                                                        impulses to the sacral spinal cord. The increased level of activity
                                                                        in the fibers (1) facilitates parasympathetic motor neurons in
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