Page 233 - Fundamentals of anatomy physiology
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220  Unit 2  Support and Movement                              6-7    Exercise, hormones,
    Figure 6–13  The Blood Supply to a Mature Bone.
                                                                   and nutrition affect bone development
                Vessels in Bone                      Articular     and the skeletal system
                       Epiphyseal                    cartilage
                                                                   Learning Outcome  Discuss the effects of exercise, hormones,
                  artery and vein                                  and nutrition on bone development and on the skeletal system.

                     Metaphyseal                                   What factors have the most important effects on the processes
                  artery and vein                                  of bone remodeling? Exercise, nutrition, and hormones are key.

	6          Branches of                              Periosteum    The Effects of Exercise on Bone
         nutrient artery
                                                     Compact       The turnover and recycling of minerals give each bone the
                 and vein                            bone          ability to adapt to new stresses. The sensitivity of osteoblasts
                                                                   to electrical events has been theorized as the mechanism
        Nutrient artery                              Medullary     that controls the internal organization and structure of bone.
                and vein                             cavity        Whenever a bone is stressed, the mineral crystals generate min-
                                                                   ute electrical fields. Osteoblasts are apparently attracted to
              Periosteal                             Nutrient      these electrical fields and, once in the area, begin to produce
    arteries and veins                               foramen       bone. This finding has led to the successful use of small elec-
                                                                   tric fields in stimulating bone healing.
    Periosteum
                                                                        Because of their adaptability, bone shapes reflect the
                  Connections to                     Metaphysis    forces applied to them. For example, bumps and ridges on
                superficial osteons                                the surface of a bone mark the sites where tendons are at-
                                                     Epiphyseal    tached. If muscles become more powerful, the correspond-
                     Metaphyseal                     line          ing bumps and ridges enlarge to withstand the increased
                   artery and vein                                 forces. Heavily stressed bones become thicker and stron-
                                                                   ger, and bones that are not subjected to ordinary stresses
    complications in the aftermath of the Chernobyl nuclear reac-  become thin and brittle. For this reason, regular exercise is
    tor incident in 1986. Radioactive compounds released in the    an important stimulus for maintaining normal bone struc-
    meltdown of the reactor were deposited into the bones of ex-   ture. Champion weight lifters typically have massive bones
    posed individuals. Over time, the radiation released by their  with thick, prominent ridges. In nonathletes (especially
    own bones has caused thyroid cancers, leukemia (cancer of the  “couch potatoes”), moderate amounts of physical activ-
    blood cells, which starts in the red bone marrow), and other   ity and weight-bearing activities are essential for stimulat-
    potentially fatal cancers.                                     ing normal bone maintenance and maintaining adequate
                                                                   bone strength.
        Checkpoint
        	12.	 Describe bone remodeling.                                 Degenerative changes in the skeleton take place after rela-
        	13.	 Explain how heavy-metal ions could be incorporated   tively brief periods of inactivity. For example, you may use a
                                                                   crutch to take weight off an injured leg while you wear a cast.
              into bone matrix.                                    After a few weeks, your unstressed bones can lose up to a third
                                                                   of their mass. The bones rebuild just as quickly when you re-
         See the blue Answers tab at the back of the book.         sume normal weight loading. However, the removal of cal-
                                                                   cium salts can be a serious health hazard both for astronauts
                                                                   remaining in a weightless environment and for bedridden or
                                                                   paralyzed patients who spend months or years without stress-
                                                                   ing their skeleton.

                                                                   Nutritional and Hormonal Effects on Bone

                                                                   Normal bone growth and maintenance depend on a combina-
                                                                   tion of nutritional and hormonal factors, such as:
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