Page 752 - Fundamentals of anatomy physiology
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Chapter 20 The Heart  739

Figure 20–20  Factors Affecting Cardiac Output.                    heart transplant continues to beat unless it is kept chilled in a
                                                                   preservation solution.

Factors Affecting                   Factors Affecting              Autonomic Innervation
 Heart Rate (HR)                   Stroke Volume (SV)
                                                                   The sympathetic and parasympathetic divisions of the auto-

Autonomic                Hormones  End-diastolic  End-systolic     nomic nervous system innervate the heart by means of the nerve
innervation                           volume         volume        network known as the cardiac plexus (Figure 16–8, p. 574, and

                                                                   Figure 20–21). Postganglionic sympathetic neurons are located

HEART RATE (HR)                    STROKE VOLUME (SV) ‫ ؍‬EDV ؊ ESV  in the cervical and upper thoracic ganglia. The vagus nerves
                                                                   (N X) carry parasympathetic preganglionic fibers to small gan-

                                                                   glia in the cardiac plexus. Both ANS divisions innervate the SA

                                                                   and AV nodes and the atrial muscle cells. Both divisions also

                                                                   innervate ventricular muscle cells, but sympathetic fibers far

                         CARDIAC OUTPUT (CO) ‫ ؍‬HR ؋ SV             outnumber parasympathetic fibers there.
                                                                        The cardiac centers of the medulla oblongata contain the

                                                                   autonomic headquarters for cardiac control. p. 496 The

                                                                   cardioacceleratory center controls sympathetic neurons that

                                                                            increase the heart rate. The adjacent cardioinhibi-

Figure 20–21  Autonomic Innervation of the Heart.                           tory center controls the parasympathetic neurons
                                                                            that slow the heart rate. Reflex pathways regulate the

                                                        Vagal nucleus       cardiac centers. They also receive input from higher
                                                                            centers, especially from the parasympathetic and
Cardioinhibitory                                                            sympathetic headquarters in the hypothalamus.
            center

Cardioacceleratory                                                          &T i p s T r i c k s
                 center                                                       To remember the effect of the sympathetic ner-

                                                        Medulla               vous system on cardiac performance, remember            	20
                                                        oblongata             that sympathetic input speeds and strengthens

                                                        Vagus (N X)           the heartbeat.

    Sympathetic                                            Spinal cord      Cardiac Reflexes. Information about the status
                                                                            of the cardiovascular system arrives over visceral
   Sympathetic                                          Parasympathetic     sensory fibers accompanying the vagus nerve and
  preganglionic                                                             the sympathetic nerves of the cardiac plexus. The
                                                           Parasympathetic  cardiac centers monitor baroreceptors and che-
              fiber                                        preganglionic    moreceptors innervated by the glossopharyngeal
Sympathetic ganglia                                        fiber            (N IX) and vagus (N X) nerves. pp. 525, 526 On
(cervical ganglia and                                      Synapses in      the basis of the information received, the cardiac
                                                           cardiac plexus   centers adjust the heart’s activity to maintain ad-
    superior thoracic                                      Parasympathetic  equate circulation to vital organs, such as the brain.
      ganglia [ T1–T4])                                    postganglionic
          Sympathetic                                      fibers                The cardiac centers respond to changes in blood
                                                                            pressure as reported by baroreceptors, and to changes
 postganglionic fiber                                                       in arterial concentrations of dissolved oxygen and
                                                                            carbon dioxide as reported by chemoreceptors. For
        Cardiac nerve                                                       example, a decline in blood pressure or oxygen con-
                                                                            centrations or an increase in carbon dioxide levels
                                                                            generally means that the heart must work harder to
                                                                            meet the demands of peripheral tissues. The cardiac
                                                                            centers then call for an increase in cardiac activity.
                                                                            We detail these reflexes and their effects on the heart
                                                                            and peripheral vessels in Chapter 21.
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