Page 855 - Fundamentals of anatomy physiology

842 Unit 4 Fluids and Transport
Figure 22–26 An Integrated Summary of the Immune Response.

Antigens
Trigger

Innate (Nonspecific) Immunity

Complement NK cells, Adaptive (Specific) Immunity
system Macrophages
Antigen presentation
by APCs

Cell-Mediated Immunity Antibody-Mediated Immunity
Indicates that the
Antigen and cell is infected or Antigen and Indicates the
Class I MHC otherwise abnormal Class II MHC presence of
Protein Protein pathogens, toxins,
or foreign proteins

CD8 T cells CD4 T cells

22

Cytotoxic T Cells Memory Tc Cells Suppressor T Cells Helper T Cells Memory TH Cells
Moderate immune
Attack and Await response by Stimulate immune Await
destroy infected reappearance T cells and B cells response by T cells reappearance of
and abnormal cells of the antigen and B cells the antigen
displaying antigen Inhibition

Inhibition

Direct physical Activation Production of
and chemical of B cells memory B cells
attack
Production of
Direct physical plasma cells
and chemical
attack Secretion of
antibodies
Attack by Destruction
circulating of Antigens
proteins