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CHAPTER 4                  Lipids                                                        73

                             more health benefits than those from arachidonic acid; EPA eicosanoids help lower blood
                             pressure, prevent blood clot formation, protect against arrhythmia, and reduce inflamma-
                             tion (Rolfes, Pinna, and Whitney, 2009). Prostaglandins made from arachidonic acid are
                             responsible for the inflammatory response (IFICF, 2011).
                           ■ EPA and DHA may play a role in preventing and treating heart disease through their
                             anti-inflammatory, antiarrhythmic, and anticlotting effects (IFICF, 2009). They are
                             essential for normal growth and development. DHA, in particular, is abundant in the
                             structural lipids in the brain and in retinal membranes.

Phospholipids

Phospholipids: a           Like triglycerides, phospholipids have a glycerol backbone with fatty acids attached. What
group of compound          makes them different from triglycerides is that a phosphate group replaces one of the fatty
lipids that is similar     acids. Although phospholipids occur naturally in almost all foods, they make up a very small
to triglycerides in that   percentage of total fat intake.
they contain a glycerol
molecule and two                Phospholipids are both fat soluble (because of the fatty acids) and water soluble
fatty acids. In place of   (because of the phosphate group), a unique feature that enables them to act as emulsifiers.
the third fatty acid,      This role is played out in the body as they emulsify fats to keep them suspended in blood
phospholipids have a       and other body fluids. As a component of all cell membranes, phospholipids not only pro-
phosphate group and        vide structure but also help to transport fat-soluble substances across cell membranes. Phos-
a molecule of choline      pholipids are also precursors of prostaglandins.
or another nitrogen-
containing compound.            Lecithin is the best-known phospholipid. Claims that it lowers blood cholesterol;
                           improves memory; controls weight; and cures arthritis, hypertension, and gallbladder prob-
Emulsifier: a stabiliz-    lems are unfounded. Studies show no benefit from taking supplements because lecithin is
ing compound that          digested in the gastrointestinal tract into its component parts and is not absorbed intact to
helps to keep both         perform super functions. Lecithin is not even an essential nutrient because it is synthesized
parts of an emulsion       in the body. Many people who take lecithin supplements do not realize that they provide
(oil and water mixture)    9 cal/g, just like all other fats.
from separating.

Cholesterol

Sterols: one of three      Cholesterol is a sterol, a waxy substance whose carbon, hydrogen, and oxygen molecules
main classes of lipids     are arranged in a ring. Cholesterol occurs in the tissues of all animals. It is found in all
that include cholesterol,  cell membranes and in myelin. Brain and nerve cells are especially rich in cholesterol. The
bile acids, sex hormones,  body synthesizes bile acids, steroid hormones, and vitamin D from cholesterol. Although
the adrenocortical hor-    cholesterol is made from acetyl-coenzyme A (acetyl-CoA), the body cannot break down
mones, and vitamin D.      cholesterol into CoA molecules to yield energy, so cholesterol does not provide calories.

                                   QUICK BITE

                           Cholesterol content of selected foods

                           Beef brains, 3 oz       Cholesterol (mg)  Shrimp, 4           Cholesterol (mg)
                           Beef liver, 3 oz              1746        Whole milk, 1 cup          37
                           Beef kidney, 3 oz               375       2% milk, 1 cup             30
                           Egg yolk, 1                     329       Butter, 1 tbsp             15
                           Broiled lobster, 1 cup          213       Nonfat milk, 1 cup         12
                           Broiled steak, 4 oz             110       Egg whites                  7
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