Biopharmaceutics modeling and simulations :
Sugano, Kiyohiko.
Biopharmaceutics modeling and simulations : theory, practice, methods, and applications / Kiyohiko Sugano. - Hoboken, N.J. : John Wiley & Sons, c2012. - xxxv, 483 p. : ill. ; 24 cm.
Includes bibliographical references and index.
Introduction -- Theoretical framework I : solubility -- Theoretical framework II : dissolution -- Theoretical framework III : biological membrane permeation -- Theoretical framework IV : gastrointestinal transit models and integration -- Physiology of gastrointestinal tract and other administration sites in humans and animals -- Drug parameters -- Validation of mechanistic models -- Bioequivalence and biopharmaceutical classification system -- Dose and particle size dependency -- Enabling formulations -- Food effect -- Biopharmaceutical modeling for miscellaneous cases -- Intestinal transporters -- Strategy in drug discovery and development -- Epistemology of biopharmaceutical modeling and good simulation practice.
9781118028681 (cloth)
Biopharmaceutics--methods.
Computer Simulation.
Drug Compounding--methods.
Models, Theoretical.
RM301.4 / .S84 2012
615.7 / SKB
Biopharmaceutics modeling and simulations : theory, practice, methods, and applications / Kiyohiko Sugano. - Hoboken, N.J. : John Wiley & Sons, c2012. - xxxv, 483 p. : ill. ; 24 cm.
Includes bibliographical references and index.
Introduction -- Theoretical framework I : solubility -- Theoretical framework II : dissolution -- Theoretical framework III : biological membrane permeation -- Theoretical framework IV : gastrointestinal transit models and integration -- Physiology of gastrointestinal tract and other administration sites in humans and animals -- Drug parameters -- Validation of mechanistic models -- Bioequivalence and biopharmaceutical classification system -- Dose and particle size dependency -- Enabling formulations -- Food effect -- Biopharmaceutical modeling for miscellaneous cases -- Intestinal transporters -- Strategy in drug discovery and development -- Epistemology of biopharmaceutical modeling and good simulation practice.
9781118028681 (cloth)
Biopharmaceutics--methods.
Computer Simulation.
Drug Compounding--methods.
Models, Theoretical.
RM301.4 / .S84 2012
615.7 / SKB