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CHAPTER CONTENTS
VULVA 681 Endometriosis 689 Ectopic Pregnancy 701
Vulvitis 681 Abnormal Uterine Bleeding 690 Gestational Trophoblastic Disease 701
Non-neoplastic Epithelial Proliferative Lesions of the Hydatidiform Mole: Complete and
Disorders 682 Endometrium and Myometrium 691 Partial 701
Lichen Sclerosus 682 Endometrial Hyperplasia 691
Invasive Mole 702
Lichen Simplex Chronicus 682 Endometrial Carcinoma 692
Tumors 683 Gestational Choriocarcinoma 703
Condylomas 683 Endometrial Polyps 693
Placental Site Trophoblastic Tumor 703
Carcinoma of the Vulva 683 Leiomyoma 693 Preeclampsia/Eclampsia (Toxemia of
Pregnancy) 703
Extramammary Paget Disease 683 Leiomyosarcoma 694 BREAST 704
VAGINA 684 FALLOPIAN TUBES 695 Fibrocystic Changes 705
Vaginitis 684 OVARIES 695 Nonproliferative Changes 705
Malignant Neoplasms 684 Follicle and Luteal Cysts 695
Squamous Cell Carcinoma 684 Polycystic Ovarian Disease 695 Proliferative Change 705
Tumors of the Ovary 696
Clear Cell Adenocarcinoma 685 Surface Epithelial Tumors 696 Relationship of Fibrocystic Changes to Breast
Carcinoma 706
Sarcoma Botryoides 685 Serous Tumors 697 Inflammatory Processes 707
CERVIX 685 Tumors of the Breast 707
Cervicitis 685 Mucinous Tumors 697 Fibroadenoma 707
Neoplasia of the Cervix 685
Invasive Carcinoma of the Cervix 687 Endometrioid Tumors 698 Phyllodes Tumor 707
Endocervical Polyp 689 Brenner Tumor 698 Intraductal Papilloma 708
BODY OF UTERUS 689 Other Ovarian Tumors 698
Endometritis 689 Teratomas 698 Carcinoma 708
Adenomyosis 689 DISEASES OF PREGNANCY 700 Lesions of the Male Breast 714
Placental Inflammations and Gynecomastia 714
Infections 701
Carcinoma 714
VULVA trauma secondary to associated intense “itching” (pruritus)
often exacerbates the primary condition.
The vulva is the external female genitalia and includes the
moist hair-bearing skin and mucosa in that region. Disor- Contact irritant eczymatous dermatitis manifests as
ders of the vulva most frequently are inflammatory, ren- well-defined erythematous weeping and crusting papules
dering them more uncomfortable than serious. Malignant and plaques (Chapter 23) and may be a reaction to urine,
tumors of the vulva, although life-threatening, are rare. soaps, detergents, antiseptics, deodorants, or alcohol.
Allergic dermatitis has a similar clinical appearance and
VULVITIS may result from allergy to perfumes; additives in creams,
lotions, and soaps; chemical treatments on clothing; and
One of the most common causes of vulvitis is reactive other antigens.
inflammation in response to an exogenous stimulus,
whether an irritant (contact irritant dermatitis) or an Vulvitis also may be caused by infections, which in this
allergen (contact allergic dermatitis). Scratching-induced setting often are sexually transmitted (Chapter 17). The
most important of these infectious agents in North America
The contributions of Drs. Susan Lester (Diseases of Breast) and are human papillomavirus (HPV), the causative agent of
Anthony Montag (Diseases of Female Genital System) are gratefully condyloma acuminatum and vulvar intraepithelial neopla-
acknowledged. sia (VIN) (discussed later); herpes simplex virus (HSV-1 or
-2), the agent of genital herpes with its characteristic