Natural products in medicinal chemistry /
Natural products in medicinal chemistry /
edited by Stephen Hanessian
- Weinheim : Wiley-VCH, [2014].
- xxi, 630 pages : illustrations ; 24 cm.
- Methods and principles in medicinal chemistry ; volume 60 .
- Methods and principles in medicinal chemistry ; volume 60 .
Includes bibliographical references and index.
Natural products as drugs and leads to drugs: an introduction and perspectives as of the end of 2012 -- Natural product-derived and natural product-inspired compound collections -- Chemistry and biology of epothilones -- Taxol, taxoids, and related taxanes -- Camptothecin and analogs -- A short history of the discovery and development of naltrexone and other morphine derivatives -- Lincosamide antibacterials -- Platensimycin and platencin -- From natural product to new diabetes therapy: phlorizin and the discovery of SGLT2 inhibitor clinical candidates -- Aeruginosins as thrombin inhibitors -- Macrolides and antifungals via biotransformation -- Unnatural nucleoside analogs for antisense therapy -- Hybrid natural products -- Rethinking the role of natural products: function-oriented synthesis bryostatin, and bryologs -- Cyclopamine and congeners -- Hybrids, congeners, mimics and constrained variants spanning 30
.years of natural products chemistry: a personal retrospective
9783527332182 (hbk.) 3527332189 (hbk.)
Natural products
Organic compounds--Synthesis
Pharmaceutical chemistry
Biological Products
Chemistry, Pharmaceutical
615.19 / NAP
Includes bibliographical references and index.
Natural products as drugs and leads to drugs: an introduction and perspectives as of the end of 2012 -- Natural product-derived and natural product-inspired compound collections -- Chemistry and biology of epothilones -- Taxol, taxoids, and related taxanes -- Camptothecin and analogs -- A short history of the discovery and development of naltrexone and other morphine derivatives -- Lincosamide antibacterials -- Platensimycin and platencin -- From natural product to new diabetes therapy: phlorizin and the discovery of SGLT2 inhibitor clinical candidates -- Aeruginosins as thrombin inhibitors -- Macrolides and antifungals via biotransformation -- Unnatural nucleoside analogs for antisense therapy -- Hybrid natural products -- Rethinking the role of natural products: function-oriented synthesis bryostatin, and bryologs -- Cyclopamine and congeners -- Hybrids, congeners, mimics and constrained variants spanning 30
.years of natural products chemistry: a personal retrospective
9783527332182 (hbk.) 3527332189 (hbk.)
Natural products
Organic compounds--Synthesis
Pharmaceutical chemistry
Biological Products
Chemistry, Pharmaceutical
615.19 / NAP