Natural products in medicinal chemistry / edited by Stephen Hanessian

Contributor(s): Hanessian, Stephen [ editor.]Material type: TextTextLanguage: English Series: Methods and principles in medicinal chemistry ; volume 60Publication details: Weinheim : Wiley-VCH, [2014]Description: xxi, 630 pages : illustrations ; 24 cmContent type: 36 ISBN: 9783527332182 (hbk.); 3527332189 (hbk.)Subject(s): Natural products | Organic compounds -- Synthesis | Pharmaceutical chemistry | Biological Products | Chemistry, PharmaceuticalDDC classification: 615.19
Contents:
Natural products as drugs and leads to drugs: an introduction and perspectives as of the end of 2012 -- Natural product-derived and natural product-inspired compound collections -- Chemistry and biology of epothilones -- Taxol, taxoids, and related taxanes -- Camptothecin and analogs -- A short history of the discovery and development of naltrexone and other morphine derivatives -- Lincosamide antibacterials -- Platensimycin and platencin -- From natural product to new diabetes therapy: phlorizin and the discovery of SGLT2 inhibitor clinical candidates -- Aeruginosins as thrombin inhibitors -- Macrolides and antifungals via biotransformation -- Unnatural nucleoside analogs for antisense therapy -- Hybrid natural products -- Rethinking the role of natural products: function-oriented synthesis bryostatin, and bryologs -- Cyclopamine and congeners -- Hybrids, congeners, mimics and constrained variants spanning 30 .years of natural products chemistry: a personal retrospective
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615.19 NAP (Browse shelf (Opens below)) Available C - 11 40414
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Includes bibliographical references and index.

Natural products as drugs and leads to drugs: an introduction and perspectives as of the end of 2012 -- Natural product-derived and natural product-inspired compound collections -- Chemistry and biology of epothilones -- Taxol, taxoids, and related taxanes -- Camptothecin and analogs -- A short history of the discovery and development of naltrexone and other morphine derivatives -- Lincosamide antibacterials -- Platensimycin and platencin -- From natural product to new diabetes therapy: phlorizin and the discovery of SGLT2 inhibitor clinical candidates -- Aeruginosins as thrombin inhibitors -- Macrolides and antifungals via biotransformation -- Unnatural nucleoside analogs for antisense therapy -- Hybrid natural products -- Rethinking the role of natural products: function-oriented synthesis bryostatin, and bryologs -- Cyclopamine and congeners -- Hybrids, congeners, mimics and constrained variants spanning 30
.years of natural products chemistry: a personal retrospective

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