Applied biopharmaceutics & pharmacokinetics / Leon Shargel, Susanna Wu-Pong, Andrew B.C. Yu.

By: Shargel, Leon, 1941-Contributor(s): Wu-Pong, Susanna | Yu, Andrew B. C, 1945-Material type: TextTextLanguage: English Publication details: New York : London : McGraw-Hill, 2012Edition: .6th ed, International edDescription: xx, 811 p. : ill. ; 24 cmContent type: ISBN: 9780071603935 (hardcover : alk. paper); 007160393X (hardcover : alk. paper); 9781259011115Other title: Applied biopharmaceutics and pharmacokineticsSubject(s): Biopharmaceutics | Pharmacokinetics | Models, ChemicalDDC classification: 615.7 LOC classification: RM301.4 | .S52 2012
Contents:
Introduction to biopharmaceutics and pharmacokinetics -- Mathematic fundamentals in pharmacokinetics -- One-compartment open model: intravenous bolus administration -- Multicompartmental models : intravenous bolus administration -- Intravenous infusion -- Drug elimination and clearance -- Pharmacokinetics of oral absorption -- Multiple-dosage regimens -- Nonlinear pharmacokinetics -- Physiologic drug distribution and protein binding -- Drug elimination and hepatic clearance -- Pharmacogenetics -- Physiologic factors related to drug absorption -- Biopharmaceutic considerations in drug product design and in vitro drug product performance -- Drug product performance, in vivo : bioavailability and bioequivalence -- Impact of drug product quality and biopharmaceutics on clinical efficacy -- Modified-release drug products -- Targeted drug delivery systems and biotechnology products -- Relationship between pharmacokinetics and pharmacodynamics -- Application of pharmacokinetics to clinical situations -- Dosage adjustment in renal and hepatic disease.
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Item type Current library Home library Call number Status Notes Date due Barcode Item holds
Books Books BUC
BUC
615.7 SLA (Browse shelf (Opens below)) Available D - 13 43224
Books Books BUC
BUC
615.7 SLA (Browse shelf (Opens below)) Available D - 13 43225
Books Books BUC
BUC
615.7 SLA (Browse shelf (Opens below)) Available D - 13 43226
Books Books BUC
BUC
615.7 SLA (Browse shelf (Opens below)) Available D - 13 43227
Books Books BUC
BUC
615.7 SLA (Browse shelf (Opens below)) Available D - 13 43228
Books Books BUC
BUC
615.7 SLA (Browse shelf (Opens below)) Available D - 13 43223
Books Books BUC
BUC
615.7 SLA (Browse shelf (Opens below)) Available D - 13 40605
Total holds: 0

Includes bibliographical references and index.

Introduction to biopharmaceutics and pharmacokinetics -- Mathematic fundamentals in pharmacokinetics -- One-compartment open model: intravenous bolus administration -- Multicompartmental models : intravenous bolus administration -- Intravenous infusion -- Drug elimination and clearance -- Pharmacokinetics of oral absorption -- Multiple-dosage regimens -- Nonlinear pharmacokinetics -- Physiologic drug distribution and protein binding -- Drug elimination and hepatic clearance -- Pharmacogenetics -- Physiologic factors related to drug absorption -- Biopharmaceutic considerations in drug product design and in vitro drug product performance -- Drug product performance, in vivo : bioavailability and bioequivalence -- Impact of drug product quality and biopharmaceutics on clinical efficacy -- Modified-release drug products -- Targeted drug delivery systems and biotechnology products -- Relationship between pharmacokinetics and pharmacodynamics -- Application of pharmacokinetics to clinical situations -- Dosage adjustment in renal and hepatic disease.

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