Biopharmaceutics modeling and simulations : theory, practice, methods, and applications / Kiyohiko Sugano.
Material type:
Item type | Current library | Home library | Call number | Status | Notes | Date due | Barcode | Item holds |
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BUC | BUC | 615.7 SKB (Browse shelf (Opens below)) | Available | D - 13 | 43442 |
Includes bibliographical references and index.
Introduction -- Theoretical framework I : solubility -- Theoretical framework II : dissolution -- Theoretical framework III : biological membrane permeation -- Theoretical framework IV : gastrointestinal transit models and integration -- Physiology of gastrointestinal tract and other administration sites in humans and animals -- Drug parameters -- Validation of mechanistic models -- Bioequivalence and biopharmaceutical classification system -- Dose and particle size dependency -- Enabling formulations -- Food effect -- Biopharmaceutical modeling for miscellaneous cases -- Intestinal transporters -- Strategy in drug discovery and development -- Epistemology of biopharmaceutical modeling and good simulation practice.
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